Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms

BACKGROUND AND PURPOSE: Cannabinoid receptor activation induces prostate carcinoma cell (PCC) apoptosis, but cannabinoids other than Δ(9)-tetrahydrocannabinol (THC), which lack potency at cannabinoid receptors, have not been investigated. Some of these compounds antagonize transient receptor potenti...

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Autors principals: De Petrocellis, Luciano, Ligresti, Alessia, Schiano Moriello, Aniello, Iappelli, Mariagrazia, Verde, Roberta, Stott, Colin G, Cristino, Luigia, Orlando, Pierangelo, Di Marzo, Vincenzo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
Matèries:
Research Papers with Commentaries
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570006/
https://ncbi.nlm.nih.gov/pubmed/22594963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02027.x
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