Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells

To identify genes important for hair-cell function, we conducted a mutagenic screen in zebrafish. Larvae from one mutant line, ru848, were unresponsive to acoustic stimuli and unable to balance. The mutation results in a 90% reduction in hair-cell number and partial retinal degeneration by 5 days po...

Celý popis

Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Starr, Catherine J., Kappler, James A., Chan, Dylan K., Kollmar, Richard, Hudspeth, A. J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2004
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983050/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308474100
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!