Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells
To identify genes important for hair-cell function, we conducted a mutagenic screen in zebrafish. Larvae from one mutant line, ru848, were unresponsive to acoustic stimuli and unable to balance. The mutation results in a 90% reduction in hair-cell number and partial retinal degeneration by 5 days po...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983050/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308474100 |
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