Side Chain Structure Determines Unique Physiologic and Therapeutic Properties of norUrsodeoxycholic Acid in Mdr2(−/−) Mice

24-norursodeoxycholic acid (norUDCA), a side chain–modified ursodeoxycholic acid derivative, has dramatic therapeutic effects in experimental cholestasis and may be a promising agent for the treatment of cholestatic liver diseases. We aimed to better understand the physiologic and therapeutic proper...

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Autors principals: Halilbasic, Emina, Fiorotto, Romina, Fickert, Peter, Marschall, Hanns-Ulrich, Moustafa, Tarek, Spirli, Carlo, Fuchsbichler, Andrea, Gumhold, Judith, Silbert, Dagmar, Zatloukal, Kurt, Langner, Cord, Maitra, Uday, Denk, Helmut, Hofmann, Alan F., Strazzabosco, Mario, Trauner, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569724/
https://ncbi.nlm.nih.gov/pubmed/19475687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22891
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