24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis

BACKGROUND & AIMS: Intrahepatic granuloma formation and fibrosis characterize the pathological features of Schistosoma mansoni infection. Based on previously observed substantial anti-fibrotic effects of 24-nor-ursodeoxycholic acid (norUDCA) in Abcb4/Mdr2(−/−) mice with cholestatic liver injury...

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Bibliografiska uppgifter
I publikationen:J Hepatol
Huvudupphovsmän: Sombetzki, Martina, Fuchs, Claudia D., Fickert, Peter, Österreicher, Christoph H., Mueller, Michaela, Claudel, Thierry, Loebermann, Micha, Engelmann, Robby, Langner, Cord, Sahin, Emine, Schwinge, Dorothee, Guenther, Nina D., Schramm, Christoph, Mueller-Hilke, Brigitte, Reisinger, Emil C., Trauner, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368108/
https://ncbi.nlm.nih.gov/pubmed/25463533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.11.020
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