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Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood

We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to clarify their unusual clinical presentation but were subsequently confirmed to have typical multiple scl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, Wekerle, Hartmut, Hohlfeld, Reinhard, Goebels, Norbert
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC356967/
https://ncbi.nlm.nih.gov/pubmed/14983026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308689100
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