Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients

A new paradigm has emerged relating the pathogenesis of rheumatoid arthritis (RA), focused on the balance between T helper type 17 cells and regulatory T cells (T(regs)). In humans, both subpopulations depend on transforming growth factor (TGF)-β for their induction, but in the presence of inflammat...

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Hlavní autoři: Pesce, B., Soto, L., Sabugo, F., Wurmann, P., Cuchacovich, M., López, M. N., Sotelo, P. H., Molina, M. C., Aguillón, J. C., Catalán, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569529/
https://ncbi.nlm.nih.gov/pubmed/23379428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12017
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