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Nucleus-Localized 21.5-kDa Myelin Basic Protein Promotes Oligodendrocyte Proliferation and Enhances Neurite Outgrowth in Coculture, Unlike The Plasma Membrane-Associated 18.5-kDa Isoform

The classic myelin basic protein (MBP) family of central nervous system (CNS) myelin arises from transcription start site 3 of the Golli (gene of oligodendrocyte lineage) complex and comprises splice isoforms ranging in nominal molecular mass from 14 kDa to (full-length) 21.5 kDa. We have determined...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, Graham S.T., Samborska, Bożena, Hawley, Steven P., Klaiman, Jordan M., Gillis, Todd E., Jones, Nina, Boggs, Joan M., Harauz, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569502/
https://ncbi.nlm.nih.gov/pubmed/23184356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23166
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