Nucleus-Localized 21.5-kDa Myelin Basic Protein Promotes Oligodendrocyte Proliferation and Enhances Neurite Outgrowth in Coculture, Unlike The Plasma Membrane-Associated 18.5-kDa Isoform

The classic myelin basic protein (MBP) family of central nervous system (CNS) myelin arises from transcription start site 3 of the Golli (gene of oligodendrocyte lineage) complex and comprises splice isoforms ranging in nominal molecular mass from 14 kDa to (full-length) 21.5 kDa. We have determined...

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Detalhes bibliográficos
Main Authors: Smith, Graham S.T., Samborska, Bożena, Hawley, Steven P., Klaiman, Jordan M., Gillis, Todd E., Jones, Nina, Boggs, Joan M., Harauz, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569502/
https://ncbi.nlm.nih.gov/pubmed/23184356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23166
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