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Non-Image-Forming Light Driven Functions Are Preserved in a Mouse Model of Autosomal Dominant Optic Atrophy

Autosomal dominant optic atrophy (ADOA) is a slowly progressive optic neuropathy that has been associated with mutations of the OPA1 gene. In patients, the disease primarily affects the retinal ganglion cells (RGCs) and causes optic nerve atrophy and visual loss. A subset of RGCs are intrinsically p...

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Autores principales: Perganta, Georgia, Barnard, Alun R., Katti, Christiana, Vachtsevanos, Athanasios, Douglas, Ron H., MacLaren, Robert E., Votruba, Marcela, Sekaran, Sumathi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569441/
https://ncbi.nlm.nih.gov/pubmed/23409176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056350
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