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Probing the antibody-catalyzed water-oxidation pathway at atomic resolution

Antibodies can catalyze the generation of hydrogen peroxide (H(2)O(2)) from singlet dioxygen ((1)O*(2)) and water via the postulated intermediacy of dihydrogen trioxide (H(2)O(3)) and other trioxygen species. Nine different crystal structures were determined to elucidate the chemical consequences to...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zhu, Xueyong, Wentworth, Paul, Wentworth, Anita D., Eschenmoser, Albert, Lerner, Richard A., Wilson, Ian A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307311101
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