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D-Lactate Production as a Function of Glucose Metabolism in Saccharomyces cerevisiae

Methylglyoxal, a reactive, toxic dicarbonyl, is generated by the spontaneous degradation of glycolytic intermediates. Methylglyoxal can form covalent adducts with cellular macromolecules, potentially disrupting cellular function. We performed experiments using the model organism Saccharomyces cerevi...

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Detalhes bibliográficos
Main Authors: Stewart, Benjamin J., Navid, Ali, Kulp, Kristen S., Knaack, Jennifer L. S., Bench, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569098/
https://ncbi.nlm.nih.gov/pubmed/23361949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/yea.2942
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