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D-Lactate Production as a Function of Glucose Metabolism in Saccharomyces cerevisiae

Methylglyoxal, a reactive, toxic dicarbonyl, is generated by the spontaneous degradation of glycolytic intermediates. Methylglyoxal can form covalent adducts with cellular macromolecules, potentially disrupting cellular function. We performed experiments using the model organism Saccharomyces cerevi...

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Bibliografiske detaljer
Main Authors: Stewart, Benjamin J., Navid, Ali, Kulp, Kristen S., Knaack, Jennifer L. S., Bench, Graham
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569098/
https://ncbi.nlm.nih.gov/pubmed/23361949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/yea.2942
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