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The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment

Treatment of several types of cancer such as lung, breast, prostate, and pancreas has shown notable progresses in the past decades. However, after an initial response, tumors eventually became resistant to chemotherapy. This phenomenon, known as chemoresistance, accounts for the death of most cancer...

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Main Authors: Roller, Corinna, Maddalo, Danilo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568707/
https://ncbi.nlm.nih.gov/pubmed/23403503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00010
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