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Intranasal but not intravenous delivery of the adjuvant α-galactosylceramide permits repeated stimulation of natural killer T cells in the lung

Efficient induction of antigen-specific immunity is achieved by delivering multiple doses of vaccine formulated with appropriate adjuvants that can harness the benefits of innate immune mediators. The synthetic glycolipid α-galactosylceramide (α-GalCer) is a potent activator of NKT cells, a major in...

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Detaylı Bibliyografya
Asıl Yazarlar: Courtney, Amy N., Thapa, Prakash, Singh, Shailbala, Wishahy, Ameerah M., Zhou, Dapeng, Sastry, Jagannadha
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568446/
https://ncbi.nlm.nih.gov/pubmed/21818755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041359
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