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High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y(13) receptor

While high levels of glucose and saturated fatty acids are known to have detrimental effects on beta cell function and survival, the signalling pathways mediating these effects are not entirely known. In a previous study, we found that ADP regulates beta cell insulin secretion and beta cell apoptosi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tan, Chanyuan, Voss, Ulrikke, Svensson, Siv, Erlinge, David, Olde, Björn
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer Netherlands 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568432/
https://ncbi.nlm.nih.gov/pubmed/22941026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-012-9331-6
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