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Role of pertussis toxin-sensitive G-protein, K(+) channels, and voltage-gated Ca(2+) channels in the antinociceptive effect of inosine
Inosine is the first metabolite of adenosine. It exerts an antinociceptive effect by activating the adenosine A(1) and A(2A) receptors. We have previously demonstrated that inosine exhibits antinociceptive properties in acute and chronic mice models of nociception. The aim of this study was to inves...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer Netherlands
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568425/ https://ncbi.nlm.nih.gov/pubmed/22806273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-012-9327-2 |
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