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CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

The adaptive arm of the immune system has been suggested as an important factor in brain function. However, given the fact that interactions of neurons or glial cells with T lymphocytes rarely occur within the healthy CNS parenchyma, the underlying mechanism is still a mystery. Here we found that at...

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Autores principales: Baruch, Kuti, Ron-Harel, Noga, Gal, Hilah, Deczkowska, Aleksandra, Shifrut, Eric, Ndifon, Wilfred, Mirlas-Neisberg, Nataly, Cardon, Michal, Vaknin, Ilan, Cahalon, Liora, Berkutzki, Tamara, Mattson, Mark P., Gomez-Pinilla, Fernando, Friedman, Nir, Schwartz, Michal
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568380/
https://ncbi.nlm.nih.gov/pubmed/23335631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211270110
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