Temperature-Mediated Heteroduplex Analysis for Detection of pncA Mutations Associated with Pyrazinamide Resistance and Differentiation between Mycobacterium tuberculosis and Mycobacterium bovis by Denaturing High- Performance Liquid Chromatography

The goal of this study was to apply temperature-mediated heteroduplex analysis using denaturing high-performance liquid chromatography to identify pyrazinamide (PZA) resistance in Mycobacterium tuberculosis isolates and simultaneously differentiate between M. tuberculosis and Mycobacterium bovis. Fe...

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Detalhes bibliográficos
Main Authors: Mohamed, Amr M., Bastola, Dhundy R., Morlock, Glenn P., Cooksey, Robert C., Hinrichs, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356819/
https://ncbi.nlm.nih.gov/pubmed/15004047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.3.1016-1023.2004
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