Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice

Amyloid precursor protein (APP) proteolysis is required for production of amyloid-β (Aβ) peptides that comprise β-amyloid plaques in brains of Alzheimer’s disease (AD) patients. Recent AD therapeutic interest has been directed toward a group of anti-amyloidogenic compounds extracted from plants. We...

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Hlavní autoři: Mori, Takashi, Koyama, Naoki, Guillot-Sestier, Marie-Victoire, Tan, Jun, Town, Terrence
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568151/
https://ncbi.nlm.nih.gov/pubmed/23409038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055774
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