Intravenous tPA Therapy Does Not Worsen Acute Intracerebral Hemorrhage in Mice

Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH). Surprisingly, however, the assumption that tPA will worsen I...

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Autors principals: Foerch, Christian, Rosidi, Nathanael L., Schlunk, Frieder, Lauer, Arne, Cianchetti, Flor A., Mandeville, Emiri, Arai, Ken, Yigitkanli, Kazim, Fan, Xiang, Wang, Xiaoying, van Leyen, Klaus, Steinmetz, Helmuth, Schaffer, Chris B., Lo, Eng H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568130/
https://ncbi.nlm.nih.gov/pubmed/23408937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054203
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