Intravenous tPA Therapy Does Not Worsen Acute Intracerebral Hemorrhage in Mice

Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH). Surprisingly, however, the assumption that tPA will worsen I...

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Detalhes bibliográficos
Main Authors: Foerch, Christian, Rosidi, Nathanael L., Schlunk, Frieder, Lauer, Arne, Cianchetti, Flor A., Mandeville, Emiri, Arai, Ken, Yigitkanli, Kazim, Fan, Xiang, Wang, Xiaoying, van Leyen, Klaus, Steinmetz, Helmuth, Schaffer, Chris B., Lo, Eng H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568130/
https://ncbi.nlm.nih.gov/pubmed/23408937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054203
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