DNA Methylation Analysis in the Intestinal Epithelium—Effect of Cell Separation on Gene Expression and Methylation Profile

BACKGROUND: Epigenetic signatures are highly cell type specific. Separation of distinct cell populations is therefore desirable for all epigenetic studies. However, to date little information is available on whether separation protocols might influence epigenetic and/or gene expression signatures an...

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Hauptverfasser: Jenke, Andreas C., Postberg, Jan, Raine, Timothy, Nayak, Komal M., Molitor, Malte, Wirth, Stefan, Kaser, Arthur, Parkes, Miles, Heuschkel, Robert B., Orth, Valerie, Zilbauer, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568120/
https://ncbi.nlm.nih.gov/pubmed/23409010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055636
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