DNA Methylation Analysis in the Intestinal Epithelium—Effect of Cell Separation on Gene Expression and Methylation Profile

BACKGROUND: Epigenetic signatures are highly cell type specific. Separation of distinct cell populations is therefore desirable for all epigenetic studies. However, to date little information is available on whether separation protocols might influence epigenetic and/or gene expression signatures an...

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Autori principali: Jenke, Andreas C., Postberg, Jan, Raine, Timothy, Nayak, Komal M., Molitor, Malte, Wirth, Stefan, Kaser, Arthur, Parkes, Miles, Heuschkel, Robert B., Orth, Valerie, Zilbauer, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568120/
https://ncbi.nlm.nih.gov/pubmed/23409010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055636
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