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Isoflurane Increases Neuronal Cell Death Vulnerability by Downregulating miR-214

Since accumulating evidence suggests the application of anesthetics may increase the risk of Alzheimer’s disease (AD), we investigated the cytotoxicity of inhaled general anesthesia in neurons and its underlying mechanism. Using primary cultured rat hippocampal neurons as the study model, here we sh...

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Bibliografische gegevens
Hoofdauteurs: Yan, Hailiang, Xu, Tao, Zhao, Hongfeng, Lee, Kuo-Chieh, Wang, Hoau-Yan, Zhang, Yan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568119/
https://ncbi.nlm.nih.gov/pubmed/23408966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055276
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