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Isoflurane Increases Neuronal Cell Death Vulnerability by Downregulating miR-214
Since accumulating evidence suggests the application of anesthetics may increase the risk of Alzheimer’s disease (AD), we investigated the cytotoxicity of inhaled general anesthesia in neurons and its underlying mechanism. Using primary cultured rat hippocampal neurons as the study model, here we sh...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568119/ https://ncbi.nlm.nih.gov/pubmed/23408966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055276 |
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