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Isoflurane Increases Neuronal Cell Death Vulnerability by Downregulating miR-214

Since accumulating evidence suggests the application of anesthetics may increase the risk of Alzheimer’s disease (AD), we investigated the cytotoxicity of inhaled general anesthesia in neurons and its underlying mechanism. Using primary cultured rat hippocampal neurons as the study model, here we sh...

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Detalhes bibliográficos
Main Authors: Yan, Hailiang, Xu, Tao, Zhao, Hongfeng, Lee, Kuo-Chieh, Wang, Hoau-Yan, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568119/
https://ncbi.nlm.nih.gov/pubmed/23408966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055276
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