miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops

Deubiquitinases, such as CYLD, A20 and Cezanne, have emerged as important negative regulators that balance the strength and the duration of NF-κB signaling through feedback mechanisms. However, how these serial feedback loops are simultaneously disrupted in cancers, which commonly exhibit constituti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Song, Libing, Lin, Chuyong, Gong, Hui, Wang, Chanjuan, Liu, Liping, Wu, Jueheng, Tao, Sha, Hu, Bo, Cheng, Shi-Yuan, Li, Mengfeng, Li, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567829/
https://ncbi.nlm.nih.gov/pubmed/23247627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.174
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