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Higher Methylation in Genomic DNA Indicates Incomplete Reprogramming in Induced Pluripotent Stem Cells

Pluripotent stem cells can be created successfully through the inner cell mass (ICM), nuclear transfer, and defined-factor induction. Unfortunately, the epigenetic characteristics of the cells produced are poorly understood. In this article, we compared expression levels of enzymes involved in epige...

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Bibliografiske detaljer
Main Authors: Zhou, Wenping, Wang, Kun, Ruan, Weimin, Bo, Zhang, Liu, Lifang, Cao, Zhongyang, Chai, Lianqin, Cao, GengSheng
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567703/
https://ncbi.nlm.nih.gov/pubmed/23379582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2012.0043
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