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Activity Assay of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Triple-Negative Breast Cancer Cells Using Peptide-Conjugated Magnetic Beads

Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer with limited treatment options. Epidermal growth factor receptor I (EGFR) has emerged as a promising target in TNBC. Limited success of the EGFR kinase inhibiting small molecules in clinical trials may be attributed...

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Bibliographic Details
Main Authors: Ghosh, Gargi, Yan, Xiaoliang, Kron, Stephen J., Palecek, Sean P.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567702/
https://ncbi.nlm.nih.gov/pubmed/22994968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2012.454
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