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Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array

Epidermal growth factor receptor (EGFR) signaling plays an important role in non-small cell lung cancer (NSCLC) and therapeutics targeted against EGFR have been effective in treating a subset of patients bearing somatic EFGR mutations. However, the cancer eventually progresses during treatment with...

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Detalhes bibliográficos
Main Authors: Ghosh, Gargi, Yan, Eric, Lee, Andrew G., Kron, Stephen J., Palecek, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946430/
https://ncbi.nlm.nih.gov/pubmed/20729058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2010.07.106
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