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Structural Arrangement of the Intracellular Ca(2+) Binding Domains of the Cardiac Na(+)/Ca(2+) Exchanger (NCX1.1): EFFECTS OF Ca(2+) BINDING
The cardiac Na(+)/Ca(2+) exchanger (NCX1.1) serves as the primary means of Ca(2+) extrusion across the plasma membrane of cardiomyocytes after the rise in intracellular Ca(2+) during contraction. The exchanger is regulated by binding of Ca(2+) to its intracellular domain, which contains two structur...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567668/ https://ncbi.nlm.nih.gov/pubmed/23233681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423293 |
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