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Structural Arrangement of the Intracellular Ca(2+) Binding Domains of the Cardiac Na(+)/Ca(2+) Exchanger (NCX1.1): EFFECTS OF Ca(2+) BINDING

The cardiac Na(+)/Ca(2+) exchanger (NCX1.1) serves as the primary means of Ca(2+) extrusion across the plasma membrane of cardiomyocytes after the rise in intracellular Ca(2+) during contraction. The exchanger is regulated by binding of Ca(2+) to its intracellular domain, which contains two structur...

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Detalhes bibliográficos
Main Authors: Dixit, Mrinalini, Kim, Sunghoon, Matthews, Gage F., Erreger, Kevin, Galli, Aurelio, Cobb, Charles E., Hustedt, Eric J., Beth, Albert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567668/
https://ncbi.nlm.nih.gov/pubmed/23233681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423293
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