Endothelial Nitric-oxide Synthase Activation Generates an Inducible Nitric-oxide Synthase-like Output of Nitric Oxide in Inflamed Endothelium

High levels of NO generated in the vasculature under inflammatory conditions are usually attributed to inducible nitric-oxide synthase (iNOS), but the role of the constitutively expressed endothelial NOS (eNOS) is unclear. In normal human lung microvascular endothelial cells (HLMVEC), bradykinin (BK...

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Bibliographic Details
Main Authors: Lowry, Jessica L., Brovkovych, Viktor, Zhang, Yongkang, Skidgel, Randal A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567667/
https://ncbi.nlm.nih.gov/pubmed/23255592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436022
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