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β-Arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase
A major source of “high-output” NO in inflammation is inducible nitric oxide synthase (iNOS). iNOS is primarily transcriptionally regulated and is thought to function as an uncontrolled generator of high NO. We found that iNOS in cytokine-stimulated human lung microvascular endothelial cells (HLMVEC...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Federation of American Societies for Experimental Biology
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887266/ https://ncbi.nlm.nih.gov/pubmed/20228252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-148783 |
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