β-Arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase

A major source of “high-output” NO in inflammation is inducible nitric oxide synthase (iNOS). iNOS is primarily transcriptionally regulated and is thought to function as an uncontrolled generator of high NO. We found that iNOS in cytokine-stimulated human lung microvascular endothelial cells (HLMVEC...

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Detaylı Bibliyografya
Asıl Yazarlar: Kuhr, Frank K., Zhang, Yongkang, Brovkovych, Viktor, Skidgel, Randal A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Federation of American Societies for Experimental Biology 2010
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887266/
https://ncbi.nlm.nih.gov/pubmed/20228252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-148783
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