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The effect of one additional driver mutation on tumor progression

Tumor growth is caused by the acquisition of driver mutations, which enhance the net reproductive rate of cells. Driver mutations may increase cell division, reduce cell death, or allow cells to overcome density-limiting effects. We study the dynamics of tumor growth as one additional driver mutatio...

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Detalhes bibliográficos
Main Authors: Reiter, Johannes G, Bozic, Ivana, Allen, Benjamin, Chatterjee, Krishnendu, Nowak, Martin A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567469/
https://ncbi.nlm.nih.gov/pubmed/23396615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12020
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