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ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice

ADAM15 is a disintegrin and metalloprotease recently implicated in cancer and chronic immune disorders. We have recently characterized ADAM15 as a mediator of endothelial barrier dysfunction. Whether this molecule contributes to acute inflammation has not been evaluated. The purpose of this study wa...

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Detalhes bibliográficos
Main Authors: Sun, Chongxiu, Beard, Richard S., McLean, Danielle L., Rigor, Robert R., Konia, Thomas, Wu, Mack H., Yuan, Sarah Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567368/
https://ncbi.nlm.nih.gov/pubmed/23161886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00133.2012
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