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ADAM15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity

OBJECTIVE: Endothelium dysfunction is an initiating factor in atherosclerosis. ADAM15 is a multi-domain metalloprotease recently identified as a regulator of endothelial permeability. However, whether and how ADAM15 contributes to atherosclerosis remains unknown. METHODS AND RESULTS: Genetic ablatio...

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Detalhes bibliográficos
Main Authors: Sun, Chongxiu, Wu, Mack H., Lee, Eugene S., Yuan, Sarah Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482138/
https://ncbi.nlm.nih.gov/pubmed/22904271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.252205
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