Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer

Aged (>50 years old) human immunodeficiency virus (HIV) patients are the fastest-growing segment of the HIV-infected population in the USA and despite antiretroviral therapy, HIV-associated neurocognitive disorder (HAND) prevalence has increased or remained the same among this group. Autophagy is...

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Autores principales: Fields, Jerel, Dumaop, Wilmar, Rockenstein, Edward, Mante, Michael, Spencer, Brian, Grant, Igor, Ellis, Ron, Letendre, Scott, Patrick, Christina, Adame, Anthony, Masliah, Eliezer
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567331/
https://ncbi.nlm.nih.gov/pubmed/23341224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-012-0145-7
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