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A rapid ex vivo clinical diagnostic assay for Fas receptor-induced T lymphocyte apoptosis
Deleterious mutations in genes involved in the Fas apoptosis pathway lead to Autoimmune Lymphoproliferative Syndrome (ALPS). Demonstration of an apoptosis defect is critical for the diagnosis and study of ALPS. The traditional in vitro apoptosis assay, however, requires a week of experimental proced...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567298/ https://ncbi.nlm.nih.gov/pubmed/23054345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-012-9811-z |
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