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Robustness of the Escherichia coli Signal-Transducing UTase/UR-PII Covalent Modification Cycle to Variation in the PII Concentration Requires Very Strong Inhibition of the UTase Activity of UTase/UR by Glutamine

Uridylyltransferase/Uridylyl-Removing Enzyme (UTase/UR) catalyzes uridylylation of PII and deuridylylation of PII-UMP, with both activities regulated by glutamine. In a reconstituted UTase/UR-PII cycle containing wild-type UTase/UR, the steady-state modification of PII varied from nearly complete mo...

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Detalhes bibliográficos
Main Authors: Jiang, Peng, Zhang, Yaoping, Atkinson, M. R., Ninfa, Alexander J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567259/
https://ncbi.nlm.nih.gov/pubmed/23088522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3005736
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