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Binding Efficiency of Protein-Protein Complexes

We examine the relationship between binding affinity and interface size for reversible protein-protein interactions (PPI), using cytokines from the tumor necrosis factor (TNF) superfamily and their receptors as a test case. Using surface plasmon resonance, we measured single-site binding affinities...

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Detalhes bibliográficos
Main Authors: Day, Eric S., Cote, Shaun M., Whitty, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567247/
https://ncbi.nlm.nih.gov/pubmed/23088250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301039t
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