A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

Thyroid hormone is essential for normal metabolism and development, and overt abnormalities in thyroid function lead to common endocrine disorders affecting approximately 10% of individuals over their life span. In addition, even mild alterations in thyroid function are associated with weight change...

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Asıl Yazarlar: Porcu, Eleonora, Medici, Marco, Pistis, Giorgio, Volpato, Claudia B., Wilson, Scott G., Cappola, Anne R., Bos, Steffan D., Deelen, Joris, den Heijer, Martin, Freathy, Rachel M., Lahti, Jari, Liu, Chunyu, Lopez, Lorna M., Nolte, Ilja M., O'Connell, Jeffrey R., Tanaka, Toshiko, Trompet, Stella, Arnold, Alice, Bandinelli, Stefania, Beekman, Marian, Böhringer, Stefan, Brown, Suzanne J., Buckley, Brendan M., Camaschella, Clara, de Craen, Anton J. M., Davies, Gail, de Visser, Marieke C. H., Ford, Ian, Forsen, Tom, Frayling, Timothy M., Fugazzola, Laura, Gögele, Martin, Hattersley, Andrew T., Hermus, Ad R., Hofman, Albert, Houwing-Duistermaat, Jeanine J., Jensen, Richard A., Kajantie, Eero, Kloppenburg, Margreet, Lim, Ee M., Masciullo, Corrado, Mariotti, Stefano, Minelli, Cosetta, Mitchell, Braxton D., Nagaraja, Ramaiah, Netea-Maier, Romana T., Palotie, Aarno, Persani, Luca, Piras, Maria G., Psaty, Bruce M., Räikkönen, Katri, Richards, J. Brent, Rivadeneira, Fernando, Sala, Cinzia, Sabra, Mona M., Sattar, Naveed, Shields, Beverley M., Soranzo, Nicole, Starr, John M., Stott, David J., Sweep, Fred C. G. J., Usala, Gianluca, van der Klauw, Melanie M., van Heemst, Diana, van Mullem, Alies, H.Vermeulen, Sita, Visser, W. Edward, Walsh, John P., Westendorp, Rudi G. J., Widen, Elisabeth, Zhai, Guangju, Cucca, Francesco, Deary, Ian J., Eriksson, Johan G., Ferrucci, Luigi, Fox, Caroline S., Jukema, J. Wouter, Kiemeney, Lambertus A., Pramstaller, Peter P., Schlessinger, David, Shuldiner, Alan R., Slagboom, Eline P., Uitterlinden, André G., Vaidya, Bijay, Visser, Theo J., Wolffenbuttel, Bruce H. R., Meulenbelt, Ingrid, Rotter, Jerome I., Spector, Tim D., Hicks, Andrew A., Toniolo, Daniela, Sanna, Serena, Peeters, Robin P., Naitza, Silvia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567175/
https://ncbi.nlm.nih.gov/pubmed/23408906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003266
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