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Antagonism Versus Cooperativity with TALE Cofactors at the Base of the Functional Diversification of Hox Protein Function

Extradenticle (Exd) and Homothorax (Hth) function as positive transcriptional cofactors of Hox proteins, helping them to bind specifically their direct targets. The posterior Hox protein Abdominal-B (Abd-B) does not require Exd/Hth to bind DNA; and, during embryogenesis, Abd-B represses hth and exd...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rivas, María Luisa, Espinosa-Vázquez, Jose Manuel, Sambrani, Nagraj, Greig, Stephen, Merabet, Samir, Graba, Yacine, Castelli-Gair Hombría, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567137/
https://ncbi.nlm.nih.gov/pubmed/23408901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003252
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