Antagonism Versus Cooperativity with TALE Cofactors at the Base of the Functional Diversification of Hox Protein Function

Extradenticle (Exd) and Homothorax (Hth) function as positive transcriptional cofactors of Hox proteins, helping them to bind specifically their direct targets. The posterior Hox protein Abdominal-B (Abd-B) does not require Exd/Hth to bind DNA; and, during embryogenesis, Abd-B represses hth and exd...

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Main Authors: Rivas, María Luisa, Espinosa-Vázquez, Jose Manuel, Sambrani, Nagraj, Greig, Stephen, Merabet, Samir, Graba, Yacine, Castelli-Gair Hombría, James
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567137/
https://ncbi.nlm.nih.gov/pubmed/23408901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003252
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