Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner

BACKGROUND: Variations in the blood coagulation activity, determined genetically or by medication, may alter atherosclerotic plaque progression, by influencing pleiotropic effects of coagulation proteases. Published experimental studies have yielded contradictory findings on the role of hypercoagula...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Borissoff, Julian I., Otten, Jeroen J. T., Heeneman, Sylvia, Leenders, Peter, van Oerle, René, Soehnlein, Oliver, Loubele, Sarah T. B. G., Hamulyák, Karly, Hackeng, Tilman M., Daemen, Mat J. A. P., Degen, Jay L., Weiler, Hartmut, Esmon, Charles T., van Ryn, Joanne, Biessen, Erik A. L., Spronk, Henri M. H., ten Cate, Hugo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567111/
https://ncbi.nlm.nih.gov/pubmed/23409043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055784
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