Estrogen Induction of Telomerase Activity through Regulation of the Mitogen-Activated Protein Kinase (MAPK) Dependent Pathway in Human Endometrial Cancer Cells

Given that prolonged exposure to estrogen and increased telomerase activity are associated with endometrial carcinogenesis, our objective was to evaluate the interaction between the MAPK pathway and estrogen induction of telomerase activity in endometrial cancer cells. Estradiol (E2) induced telomer...

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Bibliographic Details
Main Authors: Zhou, Chunxiao, Steplowski, Tara A., Dickens, Hallum K., Malloy, Kimberly M., Gehrig, Paola A., Boggess, John F., Bae-Jump, Victoria L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567109/
https://ncbi.nlm.nih.gov/pubmed/23409030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055730
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