Characterization of Fragile X Mental Retardation Protein Recruitment and Dynamics in Drosophila Stress Granules

The RNA-binding protein Fragile X Mental Retardation (FMRP) is an evolutionarily conserved protein that is particularly abundant in the brain due to its high expression in neurons. FMRP deficiency causes fragile X mental retardation syndrome. In neurons, FMRP controls the translation of target mRNAs...

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Autores principales: Gareau, Cristina, Houssin, Elise, Martel, David, Coudert, Laetitia, Mellaoui, Samia, Huot, Marc-Etienne, Laprise, Patrick, Mazroui, Rachid
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567066/
https://ncbi.nlm.nih.gov/pubmed/23408971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055342
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