p21(WAF1/CIP1) Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

BACKGROUND: p21(WAF1/CIP1) is a well known cyclin-dependent kinase inhibitor induced by various stress stimuli. Depending on the stress applied, p21 upregulation can either promote apoptosis or prevent against apoptotic injury. The stress-mediated induction of p21 involves not only its transcription...

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Bibliografske podrobnosti
Main Authors: Gareau, Cristina, Fournier, Marie-Josée, Filion, Christine, Coudert, Laetitia, Martel, David, Labelle, Yves, Mazroui, Rachid
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102688/
https://ncbi.nlm.nih.gov/pubmed/21637851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020254
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