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Complete Solubilization and Purification of Recombinant Human Growth Hormone Produced in Escherichia coli
High-level expression of recombinant human growth hormone (hGH) in Escherichia coli (E. coli) leads to the formation of insoluble aggregates as inclusion bodies devoid of biological activity. Until recently, significant efforts have been made to improve the recovery of active hGH from inclusion bodi...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567055/ https://ncbi.nlm.nih.gov/pubmed/23409149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056168 |
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