Multiple Genetic Alterations within the PI3K Pathway Are Responsible for AKT Activation in Patients with Ovarian Carcinoma

The phosphatidylinositol 3-kinase (PI3K)/AKT pathway is activated in multiple cancers including ovarian carcinoma (OC). However, the relative contribution of the single components within the PI3K pathway to AKT activation in OC is still unclear. We examined 98 tumor samples from Italian OC patients...

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Detalhes bibliográficos
Main Authors: De Marco, Carmela, Rinaldo, Nicola, Bruni, Paola, Malzoni, Carmine, Zullo, Fulvio, Fabiani, Fernanda, Losito, Simona, Scrima, Marianna, Marino, Federica Zito, Franco, Renato, Quintiero, Alfina, Agosti, Valter, Viglietto, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567053/
https://ncbi.nlm.nih.gov/pubmed/23408974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055362
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